Disruption of low-frequency narrowband EEG microstate networks in Parkinson's disease with mild cognitive impairment.

ABSTRACT:

Background

Electroencephalogram (EEG) microstates provide insights into large-scale brain network coordination, revealing distinct neural dynamics within specific frequency bands associated with cognitive processes and neurological disorders. Critical gaps remain regarding the abnormalities of narrowband microstate networks in Parkinson's disease with mild cognitive impairment (PD-MCI), a key prodromal stage of the development of PD dementia. Given the importance of early detection and understanding of cognitive decline in PD-MCI, this study investigated whether alterations in narrowband EEG microstate networks could serve as early electrophysiological biomarkers for cognitive decline in PD-MCI.

Method

Forty-seven individuals with PD (21 with MCI and 26 cognitively normal [P

SUBMITTER: Pei G 

PROVIDER: S-EPMC12542164 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature