Obstructive sleep apnea and the risk of sudden cardiac death: a systematic review and meta-analysis.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) has been linked to adverse cardiovascular outcomes, but its role as a risk factor for sudden cardiac death (SCD) remains uncertain. This systematic review and meta-analysis aimed to evaluate the association between OSA and SCD and assess the influence of disease severity and treatment.

Methods

A comprehensive search of PubMed, Scopus, Web of Science, and Google Scholar was conducted up to January 17, 2025. We included observational studies reporting the association between OSA and SCD. Data were pooled using a random-effects model. Subgroup analyses were performed based on apnea-hypopnea index (AHI) and CPAP treatment. A separate meta-analysis examined adjusted odds ratios (aORs). Heterogeneity was assessed using the I² statistic, and

SUBMITTER: Zou X 

PROVIDER: S-EPMC12542175 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature