Novel inflammation biomarkers in adult minimal change disease: predicting steroid-resistance and relapse.

ABSTRACT:

Introduction

The novel systemic inflammation markers are a class of indicators combining clinically common laboratory indices, reflecting the underlying immune and inflammatory status. Minimal change disease (MCD) is an important cause of idiopathic nephrotic syndrome (INS) in adults. Novel systemic inflammation markers were evaluated for their ability to predict treatment response to steroids and subsequent relapse in adult-onset MCD.

Methods

This unicentric, retrospective study included the clinical data of adult-onset INS patients who were pathologically diagnosed with MCD at Xiangya Hospital of Central South University from January 2010 to December 2021 and followed up with the patients' remission after adequate steroid treatment, starting from the time of initial comple

SUBMITTER: Zhang W 

PROVIDER: S-EPMC12542185 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature