Oxidative balance scores and overactive bladder: mediating effects of oxidative stress and inflammatory factors.

ABSTRACT:

Background

Few studies have investigated the comprehensive impact of dietary and lifestyle factors on overactive bladder (OAB). This study aimed to explore the associations of the Oxidative Balance Score (OBS) and its components-dietary OBS (DOBS) and lifestyle OBS (LOBS)-with OAB and their underlying mechanisms.

Methods

Data were extracted from the 2007-2018 National Health and Nutrition Examination Survey (NHANES). Weighted multivariate logistic regression was employed to evaluate associations between OBS/DOBS/LOBS and OAB. Mediation analyses were conducted to assess the potential mediating roles of oxidative stress and inflammatory factors.

Results

The study included 16,493 participants, including 2,950 OAB patients. Weighted multivariate analysis revealed a consis

SUBMITTER: Qin Z 

PROVIDER: S-EPMC12542190 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature