Body composition, anthropometry, and resting energy expenditure in adults with achondroplasia: a pilot study to determine best practices.

ABSTRACT:

Background

To guide recommendations for preferable body weights and energy requirements in those with achondroplasia, particularly given concern for overweight and obesity, studies of body composition, energy utilization, and health outcomes must be conducted in those with this rare (1 in 20,000-30,000 births) condition. We compared body composition using bioelectrical impedance analysis (BIA) and anthropometry against dual energy X-ray absorptiometry (DXA) as a gold standard and characterized resting energy expenditure (REE) among adults with achondroplasia in a pilot study of the feasibility and validity of these approaches and describe implications of their use in this population.

Methods

Twenty adults (9 female, 38.5 ± 6.3 years; 11 male, 35.1 ± 10.4 years) with achondro

SUBMITTER: Schulze K 

PROVIDER: S-EPMC12542460 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature