Effect of vitamin D supplementation during pregnancy and lactation on the development of infants born to Tanzanian women living with HIV: a secondary analysis of a randomised controlled trial.

ABSTRACT:

Background

Infants born to pregnant women living with HIV (WLHIV) are at greater risk for morbidity and mortality and may also have poorer developmental outcomes as compared with infants who are not exposed to HIV. Nutrition interventions in pregnancy may affect developmental outcomes.

Objectives

This study evaluated the effect of maternal vitamin D supplementation on infant development outcomes.

Design

We conducted a secondary analysis of a randomised, triple-blind, placebo-controlled trial of maternal vitamin D supplementation from June 2015 to October 2019.

Setting

Antenatal care clinics in Dar es Salaam, Tanzania.

Participants

Pregnant WLHIV and their offspring.

Interventions

Daily 3000 IU vitamin D₃ or placebo supplements taken dur

SUBMITTER: Shobanke T 

PROVIDER: S-EPMC12542544 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature