Magnitude and histopathological patterns of gestational trophoblastic disease in Africa: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Gestational trophoblastic disease, characterised by abnormal proliferation of trophoblastic tissue in the placenta during pregnancy, contributes to maternal morbidity and mortality. This study aimed to estimate the pooled prevalence and histopathological patterns of gestational trophoblastic disease in Africa, where previous studies have reported inconsistent findings.

Design

Systematic review and meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.

Data sources

We searched PubMed, ScienceDirect, Hinari and Google Scholar for studies published between January 2000 and January 2024.

Eligibility criteria

Institution-based observational studies from African countries reporting the prevalence an

SUBMITTER: Assefa EM 

PROVIDER: S-EPMC12542576 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature