Evidence of ESBL plasmid transfer and selective persistence of multiple host-associated <i>Escherichia coli</i> isolates in a chicken cecal fermentation model.

ABSTRACT: The guts of animals and humans harbor diverse microbial communities that are regularly exposed to bacteria originating from food, water, and their surroundings. Species such as Escherichia coli are adept at colonizing multiple hosts, along with surviving in the environment. By encoding pathogenic traits and transmissible forms of antimicrobial resistance (AMR), E. coli can also pose a zoonotic risk. Our understanding of the factors that govern host residency is limited. Here, we used a chicken cecal fermentation model to study survival and the AMR transfer potential of 17 host-associated extended-spectrum β-lactamase (ESBL)-producing E. coli isolates. Vessels containing chicken cecal contents were stabilized for 4 days before the addition of a cocktail comprising ESBL-

SUBMITTER: Leng J 

PROVIDER: S-EPMC12542655 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature