Evaluating the Effectiveness of Triple Therapy in Chronic Obstructive Pulmonary Disease Patients: An Asian Population-Based Survey.

ABSTRACT:

Background

The optimal treatment strategy for chronic obstructive pulmonary disease (COPD) remains debated, especially when choosing between triple therapy and long-acting beta agonist (LABA) + long-acting muscarinic antagonist (LAMA). This study aimed to develop a model that simulates real-world prescription patterns and compares the effectiveness of these two treatment options.

Methods

This population-based cohort study used Taiwan's National Health Insurance Research Database to follow COPD patients who had been on LABA plus inhaled corticosteroids (ICSs) for more than 28 days. These patients were followed until they either upgraded to triple therapy or switched to LABA plus LAMA. The study enrolled patients from 2013 to 2021. Cox proportional hazard models were used to e

SUBMITTER: Sung CY 

PROVIDER: S-EPMC12542726 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature