Modeling reveals a metabolic basis of competition among <i>Dehalobacter</i> strains during tandem chloroform and dichloromethane metabolism.

ABSTRACT: SC05-UT is an anaerobic, heterogenous microbial enrichment culture that reduces chloroform to dichloromethane through reductive dechlorination, which it further mineralizes to carbon dioxide. This dichloromethane mineralization yields electron equivalents that are used to reduce chloroform without the addition of exogenous electron donor. By studying this self-feeding chloroform-amended culture and a dichloromethane-amended enrichment subculture (named DCME), we previously found the genomic potential to perform both biodegradation steps in two distinct Dehalobacter strains: Dehalobacter restrictus SAD and Candidatus Dehalobacter alkaniphilus DAD. Though present in each enrichment culture, strain SAD is more abundant in the chloroform-fed subculture SC05-UT, while strai

SUBMITTER: Bulka O 

PROVIDER: S-EPMC12542780 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature