Reduced Functional Status among Kidney Transplant Recipients over Time and Associated Risks Post-Transplant.

ABSTRACT:

Background

Reduced functional status (RFS) has been associated with death and graft loss after kidney transplant; whether the risk of short-term outcomes, including delayed graft function (DGF) and early graft loss (EGL) is also increased is unknown. The purpose of this study was to examine whether RFS is associated with DGF, EGL, and all-cause graft loss (ACGL) in kidney transplant recipients (KTRs; overall and by recipient age, sex, race, donor status, and transplant era).

Methods

Separately among adult living and deceased donor KTR in the United States identified using the SRTR (2000-2017), multivariable logistic regression and Cox proportional hazards models were used as appropriate to examine the association of RFS (Karnofsky Performance Status [KPS] ≤50%; requires cons

SUBMITTER: Dixon SL 

PROVIDER: S-EPMC12542881 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature