ABO blood groups and cardiovascular disease and its risk in continental Africans and people of African ancestry: A systematic review.

ABSTRACT:

Background

Cardiovascular disease (CVD) remains a global health challenge and contributes substantially to mortality burden in sub-Saharan Africa (SSA) in particular. Several factors, including particular blood group types in the ABO system, have been associated with CVD risk. However, the direction of the association of ABO blood groups with CVD remains controversial. This review looked at the studies that investigated the association of ABO blood groups and CVD and its risk in SSA and people of African ancestry.

Methods

The review included all observational studies that investigated ABO blood groups and their association with CVD and CVD risk in Africans and people of African descent and were published in English between 1960 and 2023. The data were extracted from Pubmed,

SUBMITTER: Broni F 

PROVIDER: S-EPMC12543130 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature