A novel biomarker Ins60/ApoA for predicting diabetic kidney disease in newly diagnosed type 2 diabetes: a pilot study.

ABSTRACT:

Objective

We performed this cross-sectional study to explore potential biomarkers for predicting diabetic kidney disease (DKD) in newly diagnosed type 2 diabetes mellitus (T2DM).

Methods

A total of 623 patients were recruited from Xuzhou First People's Hospital and Nanjing First Hospital based on the electronic case records system. Patients were grouped according to their albuminuria-to-creatinine ratio (ACR) into two categories: ACR < 30 mg/g and ACR ≥ 30 mg/g. Biomarker levels between the two ACR groups were compared using an independent sample t-test. Correlation analysis was determined using Pearson's or Spearman's analysis and binary logistic regression. Receiver operating characteristic (ROC) curve analysis was used to elucidate the predictive effect of biomarke

SUBMITTER: Sun J 

PROVIDER: S-EPMC12546220 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature