The peritoneal cestode Taenia crassiceps restructures gut bacterial communities in the mouse host: identification of potential resistance-associated bacteria.

ABSTRACT: Helminthic parasites cause chronic infections due to their ability to generate immune regulatory networks in their hosts; however, an additional component in this interplay is the microbiota. In this regard, new insights have emerged from intestinal helminthic infections, but whether extraintestinal worms are able to alter intestinal microbiota is unknown. Here, we explored microbiota changes occurring during experimental infection with the peritoneal, non-migrating cestode Taenia crassiceps. Our sequencing approach allowed for the identification of 56 families and 119 genera in the fecal samples. We compared the microbiota composition between wild-type (WT) and NLRP3-deficient mice (NLRP3^-/-), since we recently reported that the lack of NLRP3 dramatically enhanced mouse resista

SUBMITTER: Mateos-Arenas D 

PROVIDER: S-EPMC12546395 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature