Stage-dependent survival in gastric cancer: a Danish nationwide cohort study.

ABSTRACT:

Background

Gastric cancer remains a major clinical challenge with poor prognosis. This study investigated survival outcomes based on treatment strategy, tumor stage, and histology in Danish gastric cancer patients.

Methods

From January 2013 to December 2021, 2,156 gastric cancers were registered in the Danish Esophagogastric Cancer Group database, covering 99% of national cases. Data were analyzed for patients with intestinal and diffuse-type cancers. Survival was assessed using Kaplan-Meier curves and Cox regression, adjusting for tumor stage, treatment, and demographics.

Results

Median survival was significantly higher with surgery ± perioperative chemotherapy (SCT) than with palliative treatment. For the intestinal-type cancers, SCT resulted in a median survival of

SUBMITTER: Kempf ON 

PROVIDER: S-EPMC12546399 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature