Duodenal mucosal autotransplantation.

ABSTRACT:

Background and aims

Closure of large defects and postresection strictures can be challenging to manage after endoscopic mucosal resection (EMR) of large duodenal lesions. Duodenal mucosal autotransplantation (DAT) may offer a new strategy for defect closure and stricture prevention in patients that undergo resection of large lesions in the duodenum.

Methods

A 57-year-old female underwent piecemeal EMR of a duodenal adenoma involving 60% of the luminal circumference. A mucosal autograft (2 x 2 cm) was harvested from adjacent duodenum using standard EMR technique and fixed to the resection bed using helical tacks and hemostatic clips. This resulted in complete defect closure without luminal compromise.

Results

On follow-up EGD at 6 weeks, we noted graft incorporation, i

SUBMITTER: Kadkhodayan K 

PROVIDER: S-EPMC12546445 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature