Association of Dietary Sodium and Potassium With Blood Pressure and Proteinuria in Africans With Kidney Disease.

ABSTRACT:

Introduction

Associations of dietary sodium (Na) and potassium (K) with blood pressure (BP) show conflicting results, with limited data in individuals of African ancestry. We examined cross-sectional associations of 24-hour urine Na (UNa_24h) and K (UK_24h), proxies for dietary intake, with BP and proteinuria in CKD cohorts in West Africa and USA.

Methods

We analyzed participants in the Diet, CKD and ApolipoproteinL1 (DCA) study, an ancillary of the Human Hereditary and Health in Africa (H3Africa) Kidney Disease Study; and the Chronic Renal Insufficiency Cohort (CRIC) study. The exposures included calibrated UNa_24h, UK_24h and UNa_24h-to-UK_24h ratio. The outcomes were systolic and diastolic BP (SBP and DBP), and 2

SUBMITTER: Ilori TO 

PROVIDER: S-EPMC12546457 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature