Diagnostic value of MRI and diffusion-weighted imaging in dysthyroid optic neuropathy: a cross-sectional study providing insights into predictive parameters and pathogenesis.

ABSTRACT:

Purpose

To compare magnetic resonance imaging (MRI) and clinical characteristics between patients with moderate-to-severe Graves orbitopathy (GO) and dysthyroid optic neuropathy (DON), and to assess the diagnostic value of these factors for DON.

Methods

Monocentric prospective cross-sectional study. Thirty-four orbits with DON and 62 orbits with moderate-to-severe GO were included. Patients were older than 18 years, had never undergone surgical decompression, and did not receive glucocorticoid or radiotherapy within 6 months prior to participation. A standardized orbital MRI protocol was performed followed by ophthalmic and orthoptic examination within 4 weeks. Main outcome measures were: maximal radial diameter of the extraocular muscles (EOMs), signal intensity ratio of th

SUBMITTER: Potvin ARGG 

PROVIDER: S-EPMC12546493 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature