Correlations between hemodynamics and radiomic features in thrombosed intracranial aneurysms.

ABSTRACT:

Purpose

Evaluating intracranial aneurysm (IA) rupture risk is essential for guiding management. Although intrasaccular thrombosis (IST) is less common, it can contribute to aneurysm growth, mass effect, and rupture. Aneurysm wall enhancement (AWE) on high-resolution MRI (HR-MRI) offers valuable insight into IST and IA progression. Using radiomics, we extracted spatial information of the aneurysm wall to characterize AWE. This study aimed to explore correlations between radiomics-based AWE profiles and gross hemodynamic parameters, integrating imaging and flow dynamics to better understand IST.

Methods

Radiomic analysis was conducted on a cohort of 3T HR-MRI scans from IA with IST. Three-dimensional vascular reconstructions and CFD simulations were conducted to quantify hemod

SUBMITTER: Lyu Z 

PROVIDER: S-EPMC12546522 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature