Heat Stress Nephropathy in CKD of Uncertain Etiology Hotspots of Bargarh District Odisha, India.

ABSTRACT:

Introduction

Repeated heat exposure, physical exertion, and inadequate hydration can cause acute kidney injury (AKI), potentially progressing to chronic kidney disease (CKD). However, cohort-level research on heat stress as a contributing factor remains limited. This study investigates occupational heat exposure among farming communities in hotspot villages of Bargarh district, Odisha, India.

Methods

A cross-sectional study of 1136 participants was conducted in Bargarh district to assess heat stress nephropathy among agricultural workers. Based on Sri Lankan criteria, heat stress nephropathy was defined by albumin-creatinine ratio ≥ 30 mg/g, no known CKD causes, urine specific gravity ≥ 1.03, and signs of tubulointerstitial nephritis. Heat stress index, serological tests, an

SUBMITTER: Biswas P 

PROVIDER: S-EPMC12546656 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature