Plant-Based Diet Quality, Healthy Lifestyle, and Dementia Risk in Older Adults With Cardiometabolic Diseases.

ABSTRACT:

Background

Cardiometabolic diseases (CMDs; heart disease, stroke, and type 2 diabetes) are associated with dementia risk, but whether a healthy plant-based diet and other lifestyle behaviors can mitigate this risk is unclear.

Objectives

The purpose of this study was to investigate joint associations of CMDs, plant-based diet quality, and other lifestyle behaviors with dementia risk.

Methods

Dementia-free UK Biobank participants aged ≥55 years with two or more 24-hour dietary recalls were included (N = 71,648). The plant-based diet index (PDI), healthful PDI (hPDI), and unhealthful PDI (uPDI) were calculated according to consumption of 17 food groups. Prevalent CMDs and incident dementia were determined from medical records. A healthy lifestyle beyond diet was defined

SUBMITTER: Dunk MM 

PROVIDER: S-EPMC12546824 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature