Twelve-month Results From the Percutaneous Endoscopic Benign Biliary Laser Stricturotomy Study: A Prospective Single-Arm Pilot Trial Evaluating Safety and Efficacy.

ABSTRACT:

Background and aims

Benign biliary strictures (BBSs) are associated with poor long-term patency, substantial morbidity, and high health-care costs. Despite a multitude of available treatment options-peroral endoscopic, percutaneous transhepatic, and surgical reconstruction-recurrence rates remain high. This study assesses the safety and efficacy of percutaneous transhepatic cholangioscopy (PTCS)-assisted holmium laser stricturotomy for BBS management.

Methods

The Percutaneous Endoscopic Benign Biliary Laser study is a prospective, single-arm, open-label pilot trial conducted at a single academic institution. Between October 2022 and August 2023, 5 patients with BBSs underwent PTCS-assisted laser stricturotomy, with or without lithotripsy, using a holmium:yttrium-aluminum-gar

SUBMITTER: Roberts DG 

PROVIDER: S-EPMC12546874 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature