Bioengineered human blood vessels to treat hospital-acquired vascular complications.

ABSTRACT:

Background

Complications of vascular surgery and vascular procedures, including iatrogenic injuries, planned oncological tumor resections, and steal syndrome after arteriovenous access placement, are increasingly common in modern medical care. Harvesting of autologous vein to address these consequences and complications produces injury to the patient, and suitable vein may not be accessible in the urgent/emergent setting.

Methods

The objective is to evaluate the performance of the acellular tissue engineered vessel (ATEV) in the repair of sequelae and complications of vascular procedures. CLN-PRO-V005 (clinicaltrials.gov NCT03005418; "V005") is a multicenter, single-arm clinical trial at 19 level I trauma centers in the United States and Israel, that evaluated the safety and

SUBMITTER: Lum Y 

PROVIDER: S-EPMC12547166 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature