Controlled Clinical Studies of Combined Oral Contraceptives for Dysmenorrhea in China: A Systematic Literature Review.

ABSTRACT:

Background

Combined oral contraceptives (COCs) can relieve dysmenorrhea, but utilization is low in Chinese women. This systematic literature review was conducted to summarize the design of clinical studies and the effectiveness and safety of COCs for dysmenorrhea in Chinese women.

Methods

The PubMed, EMBASE, CNKI, Wanfang, VIP, Chinese clinical trial register, and ClinicalTrials.gov databases were searched for randomized controlled trials (RCTs), non-RCTs, and cohort studies investigating COCs for dysmenorrhea in the Chinese population. A narrative synthesis and descriptive statistics were used to summarize the clinical study designs, intensity of dysmenorrhea symptoms, and safety of COCs for dysmenorrhea in Chinese women.

Results

Twenty-eight clinical studies (24 RCT

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12547401 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature