Bioactive Cr(III), Co(II), and Mn(II) Complexes with N'((3-Hydroxynaphthalen-2-yl)methylene)picolinohydrazide: Structural, Computational, and Biological Studies.

ABSTRACT: The present study focuses on the synthesis and characterization of novel bioactive complexes of Cr-(III), Co-(II), and Mn-(II) derived from N'-((3-hydroxynaphthalen-2-yl)-methylene)-picolinohydrazide (H₂L), a Schiff-base ligand featuring multifunctional donor sites. The primary objective was to investigate the coordination behavior, stability, and biological efficacy of these metal chelates. The complexes were synthesized via direct metal-ligand reactions and characterized using elemental analysis, FT-IR spectroscopy, UV-Vis, PXRD, ¹H NMR spectroscopy, MS, magnetic susceptibility measurements, and thermogravimetric analysis. Spectroscopic evidence supported tetrahedral geometries for the Co-(II) and Mn-(II) complexes, while the Cr-(III) complex exhibited an octahedral

SUBMITTER: Abou El-Reash YG 

PROVIDER: S-EPMC12547536 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature