Adverse Pregnancy Outcomes and Long-Term Risk of Atrial Fibrillation.

ABSTRACT:

Importance

Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risk of atrial fibrillation (AF) and potential causality are unclear. A better understanding of such risks is needed to identify women with high risk early in life and guide interventions to prevent AF and its complications.

Objective

To determine long-term risks of AF associated with 6 major adverse pregnancy outcomes in a large population-based cohort and assess for familial confounding using cosibling analyses.

Design, setting, and participants

This national cohort study included all women with a singleton delivery in Sweden between 1973 and 2015. Analyses were conducted between May 23 and August 18, 2025.

Exposures

Adverse pregnancy outcomes (pr

SUBMITTER: Crump C 

PROVIDER: S-EPMC12547675 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature