Association of prehospital pupillary diameter with return of spontaneous circulation and neurological outcome after out-of-hospital cardiac arrest: A multicenter retrospective analysis.

ABSTRACT:

Background

In Japan, emergency medical services (EMS) routinely record pupillary size and pupillary light reflex (PLR) during prehospital care for out-of-hospital cardiac arrest (OHCA). While hospital-based studies have established the prognostic value of pupillary findings, the significance of prehospital pupillary diameter remains uncertain.

Objective

To examine whether pupillary diameter at EMS contact predicts prehospital return of spontaneous circulation (ROSC) and 30-day neurological outcomes.

Methods

This retrospective cohort study analyzed SOS-KANTO 2017, a prospective multicenter OHCA registry. Of 9909 adults, 8494 were eligible after excluding those not in arrest at EMS contact or with missing data. EMS personnel, trained in neurological assessment, document

SUBMITTER: Takeda M 

PROVIDER: S-EPMC12547821 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature