Bowel Urgency Severity Among Patients with Crohn's Disease or Ulcerative Colitis on Advanced Therapies: Real-World Data Using Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease.

ABSTRACT:

Background and aims

Research on the impact of advanced therapies on bowel urgency severity in Crohn's disease (CD) and ulcerative colitis (UC) is limited. We assessed moderate-to-severe bowel urgency among patients with UC or CD at advanced therapy initiation, 6 months, and 12 months.

Methods

Data from the Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease were used. Patients newly prescribed advanced therapies for CD or UC at enrollment, who completed the bowel urgency questionnaires and remained on the same advanced therapy at enrollment and at 6 months or 12 months, were included. Demographics, clinical data, and bowel urgency severity were summarized descriptively.

Results

Overall, 532 patients with CD were included (332 on tumor necrosis

SUBMITTER: Lewis JD 

PROVIDER: S-EPMC12547891 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature