Potential Negative Feedback between Age and Baseline Axial Length on Axial Elongation in High Myopia.

ABSTRACT:

Purpose

To evaluate the axial elongation in highly myopic eyes and assess the effects of age, sex, baseline axial length (AL), cataract surgery (CS), pathologic myopia (PM), baseline intraocular pressure (IOP), and genetic risk scores (GRSs).

Design

Retrospective cohort study.

Participants

This study included 614 eyes from 367 individuals with high myopia.

Methods

The study assessed axial elongation rates and their associations with age, sex, baseline AL, CS, PM, and baseline IOP including potential interactions among these factors. Additionally, the study examined whether incorporating GRS improved the predictive model for axial elongation.

Main outcome measures

Axial elongation rate in highly myopic eyes.

Results

The study included 367 participa

SUBMITTER: Murata M 

PROVIDER: S-EPMC12547896 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature