Retinal and Choroidal Microvasculature at Different Myopia Severities: A Systematic Review and Meta-Analysis.

ABSTRACT:

Topic

This study systematically evaluates changes in retinal and choroidal microvasculature with increasing myopia severity.

Clinical relevance

Conflicting results in reported studies on the changes in retinal and choroidal microvasculature with increasing myopia severity require comprehensive analysis to guide patient management.

Methods

The PubMed, Embase, and Web of Science databases were thoroughly searched for studies published before May 8, 2025 on retinal or choroidal changes across different myopia severities. Included were studies with cross-sectional or prospective case-control and cohort designs that reported outcomes of foveal avascular zone (FAZ) area and vessel densities (VD) in the retina and choroid. The risk of bias was assessed by the Newcastle-Ottaw

SUBMITTER: Lin ZX 

PROVIDER: S-EPMC12548084 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature