Assessing the Impact of Pharmacological Pupil Dilation on Anterior Chamber Cells Counting Using OCT.

ABSTRACT:

Purpose

Anterior chamber (AC) cells are seen as hyperreflective dots (HRDs) on anterior segment OCT (AS-OCT), but many factors can affect their objective counting. The aim of this study was to evaluate the effect of pharmacological dilation with tropicamide 0.5% (T) or phenylephrine 2.5% + tropicamide 0.5% (PH + T) on the assessment of AC HRDs density measured in healthy eyes by AS-OCT.

Design

Cross-sectional, observational study.

Participants

Healthy subjects with no history of uveitis, no ocular or systemic conditions, and no recent ocular surgery.

Methods

Participants underwent comprehensive ophthalmic examinations, including single-line AS-OCT (16.5 mm; μm:pixel ratio = 8.79; Anterion, Heidelberg Engineering) imaging before (miosis) and after pupil dilation

SUBMITTER: Manni P 

PROVIDER: S-EPMC12548094 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature