Effect of early intubation on patient-centered outcomes in urosepsis: a retrospective multicenter cohort study.

ABSTRACT:

Background

Urosepsis has a reported mortality rate of up to 13.5%, and approximately 38% of affected patients require intubation. This study evaluated the association between the timing of intubation and in-hospital mortality among patients with urosepsis.

Methods

We conducted a multicenter retrospective cohort study using the Australian and New Zealand Intensive Care Registry Adult Patient Database. Adult ICU patients (≥ 16 years) with a primary diagnosis of urosepsis admitted between 1 January 2018 and 1 April 2023 were included. Patients were classified into early (≤ 24 h from ICU admission) or delayed (> 24 h) intubation groups. The primary outcome was in-hospital mortality. Secondary outcomes included ICU and hospital lengths of stay (LOS), mortality at 6, and 12 months

SUBMITTER: Suga M 

PROVIDER: S-EPMC12548251 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature