Feasibility and usefulness of in-hospital and at-home salivary sampling in healthy dogs and trilostane-treated dogs with Cushing's syndrome: a prospective observational study.

ABSTRACT:

Background

Monitoring Cushing's syndrome (CS) in dogs remains a significant challenge and currently relies on clinical signs, biochemistry results and hormone tests, such as prepill or post-ACTH cortisol. Salivary cortisol testing at home, effective in humans, could benefit dogs by minimizing in-hospital fear impacts on cortisol measurements. The objectives of this study were to (1) assess the feasibility of saliva sampling in client-owned dogs and (2) compare at-home and in-hospital salivary cortisol concentrations for monitoring trilostane treatment. Ten healthy controls and 38 trilostane-treated dogs with CS were included in this prospective observational clinical trial. Saliva was collected using a ginger-dipped Salimetrics^® swab held in the dogs' mouths for 30 secon

SUBMITTER: Meunier SM 

PROVIDER: S-EPMC12548268 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature