Aortic Pulse Wave Velocity and Extracellular Water Expansion in Hemodialysis Patients.

ABSTRACT:

Background

Pulse wave velocity (PWV), a measurement of arterial stiffness, is a risk factor for cardiovascular mortality in hemodialysis patients. Debate continues as to whether PWV is increased by volume overload. As such, we reviewed the association between volume overload and PWV.

Methods

We measured aortic PWV (aPWV) in hemodialysis patients attending routine dialysis sessions with contemporaneous measurements of extracellular water/total body water (ECW/TBW) ratios using multifrequency bioimpedance.

Results

A total of 102 patients, 63.7% male, mean age 63.5 ± 15.9 years, 44.1% diabetic, median dialysis duration 22.2 (4.9-52.8) months, weight 73.7 ± 15.8 kg, and central systolic blood pressure 157 ± 35 mmHg had a mean aPWV of 10.1 ± 2.5 m/s. Patients dialyzed with

SUBMITTER: Chhabra R 

PROVIDER: S-EPMC12548306 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature