Stable brain PET metabolic networks using a multiple sampling scheme.

ABSTRACT: Interregional communication within the human brain is essential for maintaining functional integrity. A promising approach for investigating how brain regions communicate relies on the assumption that the brain operates as a complex network. In this context, positron emission tomography (PET) images have been suggested as a valuable source for understanding brain networks. However, such networks are typically assembled through direct computation without accounting for outliers, impacting the reliability of group representative networks. In this study, we used brain [¹⁸F]fluoro-2-deoxyglucose PET data from 1,227 individuals in the Alzheimer's disease (AD) continuum from the Alzheimer's Disease Neuroimaging Initiative cohort to develop a novel method for constructing stable metabo

SUBMITTER: Schu G 

PROVIDER: S-EPMC12548669 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature