Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms.

ABSTRACT: Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbation paradigms remain, however, difficult to perform routinely. To discover alternative paradigms and metrics, we systematically explore brain stimulation and resting-state activity in a whole-brain model. We find that perturbational complexity only occurs when the brain model operates within a specific dynamical regime, in which spontaneous activity produces a large degree of functional network reorganizations referred to as being fluid. The regime of high brain fluidity is characterized by a small battery of metrics drawn from dynamical systems theory an

SUBMITTER: Breyton M 

PROVIDER: S-EPMC12549018 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature