Association of Prenatal Maternal Anxiety With Fetal Regional Brain Connectivity.

ABSTRACT:

Importance

Maternal psychological distress during pregnancy is associated with adverse obstetric outcomes and neuropsychiatric deficits in children. Currently unavailable in vivo interrogation of fetal brain function could provide critical insights into the onset and timing of altered neurodevelopmental trajectories.

Objective

To investigate the association between prenatal maternal stress, anxiety, and depression and in vivo fetal brain resting state functional connectivity.

Design, setting, and participants

This cohort study included pregnant women scanned between January 2016 and April 2019. A total of 50 pregnant women with healthy pregnancies were prospectively recruited from low-risk obstetric clinics in the Washington DC area and were scanned at Children's Nati

SUBMITTER: De Asis-Cruz J 

PROVIDER: S-EPMC12549102 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature