Comparison of US Federal and Foundation Funding of Research for Sickle Cell Disease and Cystic Fibrosis and Factors Associated With Research Productivity.

ABSTRACT:

Importance

Sickle cell disease (SCD) and cystic fibrosis (CF) are severe autosomal recessive disorders associated with intermittent disease exacerbations that require hospitalizations, progressive chronic organ injury, and substantial premature mortality. Research funding is a limited resource and may contribute to health care disparities, especially for rare diseases that disproportionally affect economically disadvantaged groups.

Objective

To compare disease-specific funding between SCD and CF and the association between funding and research productivity.

Design, setting, and participants

This cross-sectional study examined federal and foundation funding, publications indexed in PubMed, clinical trials registered in ClinicalTrials.gov, and new drug approvals from Ja

SUBMITTER: Farooq F 

PROVIDER: S-EPMC12549141 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature