Correlation of breathing task derived cerebrovascular reactivity with baseline CBF, OEF and CMRO₂.

ABSTRACT:

Rationale and objectives

Only a few studies examined the correlation between cerebrovascular reactivity (CVR) and other physiological parameters such as cerebral blood flow (CBF), oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO₂). In this study, these baseline parameters were measured using 3D MRI with whole brain coverage for the investigation of global and regional correlation between each other to enhance understanding of brain function and improve tumor diagnosis.

Materials and methods

All measurement were performed at 3 T. CVR was derived from a breath-holding task. Baseline CBF was measured by pseudo-continuous arterial spin labeling. Baseline OEF was measured with a gradient-echo sampling of spin-echo pulse sequence. T1 weighted

SUBMITTER: Zhang K 

PROVIDER: S-EPMC12549280 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature