Infant sleep EEG features at 4 months as biomarkers of neurodevelopment at 18 months.

ABSTRACT:

Background

Sleep parameters evolve in parallel with neurodevelopment. Sleep participates in synaptic homeostasis and memory consolidation and infant sleep parameters correlate with later aspects of early childhood cognition.

Methods

Typically developing, term-born infants had a diurnal sleep-EEG at 4 months and Griffiths III developmental assessment at 18 months. EEG analysis included sleep macrostructure (i.e. durations of total sleep and sleep stages, and latencies to sleep and REM), sleep spindle features, and quantitative EEG features (qEEG): interhemispheric connectivity and spectral power. We assessed the correlations between these EEG features and Griffiths III quotients.

Results

Sleep recordings from 92 infants were analyzed. Sleep latency was positively assoc

SUBMITTER: Ventura S 

PROVIDER: S-EPMC12549339 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature