Comparative analyses of dynamic transcriptome profiles reveal that DUSP1 regulates myogenic differentiation and muscle fiber type transformation.

ABSTRACT: Modern breeding strategies have engendered pronounced disparities in muscle mass and quality between indigenous chickens and specialized broilers. Despite these observable phenotypic differences, the molecular regulatory mechanisms that underpin these variations remain largely uncharacterized. The objective of this study was to elucidate the key genes and regulatory pathways that govern the differential development of pectoral muscle between indigenous chickens and specialized broilers. The differences in myofiber development between the fast-growing commercial broiler breed Arbor Acres (AA) and the slow-growing local breed Taoyuan chickens (TY) were compared through phenotypic and transcriptome sequencing of pectoral muscle development at multiple time points. Subsequently, functional val

SUBMITTER: Peng F 

PROVIDER: S-EPMC12549544 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature