Hyperbaric oxygen therapy for radiation enteritis and clinical parameters: a systematic review and meta-analysis.

ABSTRACT:

Background

Hyperbaric oxygen therapy (HBOT) has been debated regarding its efficacy and safety in treating radiation enteritis (RE), with no standardized clinical protocols established. This study evaluates the clinical evidence on the use of HBOT in the management of RE, focusing on efficacy, safety, treatment parameters, and potential mechanisms.

Methods

A comprehensive computer-based search was conducted across nine databases. The study assessed the effects of HBOT on gastrointestinal symptoms, immune function, inflammation, and its role in reducing the incidence of moderate to severe RE. Additionally, clinical application protocols were analyzed.

Results

This study analyzed data from 22 clinical studies involving 1,318 subjects, including six RCTs incorporated int

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12549627 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature