Adverse pregnancy and perinatal outcomes in women with polycystic ovary syndrome undergoing assisted reproductive technology: a systematic review and meta-analysis.

ABSTRACT:

Background

The growing application of assisted reproductive technology (ART) has enabled more women with polycystic ovary syndrome (PCOS) to achieve pregnancy. However, the causal association between PCOS and reproductive outcomes remains uncertain. This study conducted a meta-analysis of cohort studies to explore the association between PCOS and adverse pregnancy and perinatal outcomes.

Methods

A comprehensive search was carried out in PubMed, Web of Science, Embase, and the Cochrane Library to identify studies published prior to March 22, 2025. Cohort studies evaluating differences in adverse pregnancy and perinatal outcomes between women with PCOS and those without PCOS undergoing ART were included. Meta-analysis was conducted using R 4.3.2 and STATA 12.0 to estimate risk

SUBMITTER: Xie N 

PROVIDER: S-EPMC12549646 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature