Growth in neonates with congenital kidney failure requiring continuous kidney replacement therapy.

ABSTRACT:

Background

With advanced technology, survival of neonates with congenital kidney failure (CKF) requiring continuous kidney replacement therapy (CKRT) has improved. Nutrition is essential but difficult to attain as CKRT removes proteins and micronutrients, and many patients have multiple co-morbidities. Scant data exist to guide clinicians on appropriate energy requirements for growth.

Methods

We performed a retrospective study of neonates with CKF admitted to Children's of Alabama between 2016 and 2022 who required KRT within 10 days. We evaluated risk factors and growth in the 18/24 (75%) infants who survived to 90 days. Our primary and secondary outcomes were length z-score ≥  - 2 vs. <  - 2 at 90 days and weight z-score ≥  - 2 vs. <  - 2 at 90 days, respectively. Demograp

SUBMITTER: Short K 

PROVIDER: S-EPMC12549734 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature