Bioactive compounds and therapeutic potential of Salvia fruticosa Mill. leaves against microorganisms and osteosarcoma.

ABSTRACT: Many studies reported the cytotoxic effect of Salvia fruticosa Mill. (S. fruticosa) on different cancer cell lines. This study aims to investigate the methanolic extract of S. fruticosa leaves in terms of its polyphenolic content, antioxidant activity, antimicrobial activity against different microorganisms, and cytotoxic activities on the U2OS osteosarcoma cell line. Fourier Transform Infrared Spectroscopy was performed to detect the major functional groups in the extract. The extract's total carbohydrate content was found to be 45.63 ± 3.33 mg glucose equivalent, the total phenolic content was 170.68 ± 6.52 mg caffeic acid equivalent, and the total flavonoid content was 44.71 ± 5.67 mg rutin equivalent per gram of the extract. Polyphenolic bioactive compounds of the extract were identifi

SUBMITTER: Abdelmonem BH 

PROVIDER: S-EPMC12549989 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature