Unveiling the anti-inflammatory wound healing potential of Ocimum canum extract and its phytochemicals via bioassay-guided isolation, fractionation, and computational studies.

ABSTRACT: Wound healing is a complex and dynamic process that involves the coordinated efforts of various cellular and molecular mechanisms. Chronic wounds of various etiologies, such as diabetic ulcers and pressure sores, pose significant challenges to healthcare systems worldwide due to their recalcitrant nature and associated complications. Wound healing is a complex physiological process, crucial for tissue repair and regeneration. Recently, plant-derived drugs have gained considerable attention due to their potential therapeutic applications in wound healing. In this study, we have evaluated the wound-healing properties of Ocimum canum (OC-12) extract in in-vitro and in-vivo models. Initially, we used bio-assay-guided isolation approach to identify phytochemicals present in the OC-12 extract. T

SUBMITTER: Khalid A 

PROVIDER: S-EPMC12550070 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature