Platelet-Rich Plasma in the Management of Alopecia: A Systematic Review and Meta-Analysis of Clinical Evidence.

ABSTRACT:

Introduction

Alopecia is a common hair loss condition with different treatment modalities. Platelet-rich plasma (PRP), a minimally invasive autologous therapy, has emerged as a topic of interest, but its effectiveness remains debated. The present systematic review and meta-analysis aims to evaluate the safety and efficacy of PRP for alopecia.

Methods

A comprehensive search of PubMed, EMBASE, and Scopus conducted on 27 May 2025 with monthly updates until July 10 2025 identified 43 randomized controlled trials (1877 participants) assessing PRP in alopecia. Primary outcomes were changes in hair density and thickness. Secondary outcomes included side effects, hair loss, clinical improvement, patient satisfaction, recurrence, and other hair follicle metrics.

Results

Activa

SUBMITTER: Anitua E 

PROVIDER: S-EPMC12550094 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature