Phylodynamic and phylogeographic reconstruction of IBV lineages: diverse paths and determinants, one goal for control.

ABSTRACT: Infectious bronchitis virus (IBV) is a genetically diverse avian coronavirus that significantly impacts global poultry production. While IBV evolution and spread have been widely studied, most analyses lack global scope and statistical evaluation of dispersal drivers. This study investigates the population dynamics, spatiotemporal diffusion, and determinants of spread for three major IBV lineages-GI-16, GI-19, and GI-23-using a phylodynamic framework integrated with a generalized linear model (GLM). All lineages likely originated between the 1960s and 1980s, circulating at low levels before expanding under favorable conditions, often linked to introduction into naïve or poorly managed poultry systems. Temporal trends suggested lineage competition and modulation by vaccination strategies. P

SUBMITTER: Franzo G 

PROVIDER: S-EPMC12550103 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature