Intraoperative hypotension and postoperative delirium among older high-risk patients undergoing major noncardiac surgery: a retrospective single-centre cohort study.

ABSTRACT:

Background

Intraoperative hypotension has been associated with postoperative complications, but its relationship with postoperative delirium remains debated.

Methods

This single-centre retrospective cohort study included adults (≥60 yr) with ASA physical status score of 3 or 4 undergoing major noncardiac surgery, with documented Confusion Assessment Method assessments. Patients with a history of neurosurgery, stroke, dementia, or neurocognitive disorders were excluded. The primary exposure was the cumulative duration of a mean arterial pressure <65 mm Hg (minutes). The primary outcome was postoperative delirium within 7 days, diagnosed via Confusion Assessment Method. Multivariable logistic regression was used to assess the association between intraoperative hypotension and

SUBMITTER: Ettoumi I 

PROVIDER: S-EPMC12550159 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature