Prevalence and characterization of third-generation cephalosporin, carbapenem and colistin-resistant Enterobacterales isolated from clinical samples in Cambodia.

ABSTRACT:

Objectives

Despite the threat of antimicrobial resistance (AMR) worldwide, limited studies describe the situation in human infections in Cambodia. Our study aims to evaluate the current state of AMR and describe the resistance mechanisms of the main Enterobacterales responsible for various infections in Cambodia.

Methods

Between January and April 2020, 222 clinical Enterobacterales isolates were collected from routine diagnostics at the Medical Biology Laboratory of the Institut Pasteur du Cambodge, Phnom Penh. Antimicrobial susceptibility testing and resistance phenotype analysis were performed. Beta-lactamase genes bla _CTX-M , bla _SHV , bla _TEM and bla _OXA-1 were screened in isolates resistant to third

SUBMITTER: Delvallez G 

PROVIDER: S-EPMC12550295 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature